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  • Additional publications October 2013 - Epilepsie Vereniging Nederland
    A Fontaine D Heiland M Jürgens TP Leone M Magis D Paemeleire K Palmisani S Paulus W May A J Headache Pain 2013 Oct 21 14 1 86 Epub ahead of print PMID 24144382 PubMed as supplied by publisher Free Article Related citations Atrial Autonomic Innervation A Target for Interventional Antiarrhythmic Therapy Linz D Ukena C Mahfoud F Neuberger HR Böhm M J Am Coll Cardiol 2013 Oct 2 doi pii S0735 1097 13 05453 3 10 1016 j jacc 2013 09 020 Epub ahead of print PMID 24140663 PubMed as supplied by publisher Related citations Epilepsy Guidelines on vagus nerve stimulation for epilepsy Dugan P Devinsky O Nat Rev Neurol 2013 Nov 9 11 611 2 doi 10 1038 nrneurol 2013 211 Epub 2013 Oct 15 No abstract available PMID 24126624 PubMed in process Related citations Activation of signaling pathways downstream of the brain derived neurotrophic factor receptor TrkB in the rat brain by vagal nerve stimulation and antidepressant drugs Carreno FR Frazer A Int J Neuropsychopharmacol 2013 Oct 8 1 12 Epub ahead of print PMID 24103847 PubMed as supplied by publisher Related citations Similar effects of vagus nerve stimulation and atrial ganglionated plexi stimulation on ventricular effective refractory period and action potential duration in canine He B Lu Z He W Huang B Jiang H Int J Cardiol 2013 Oct 12 168 5 5116 8 doi 10 1016 j ijcard 2013 07 237 Epub 2013 Aug 2 No abstract available PMID 23968715 PubMed in process Related citations Efficacy of vagus nerve stimulation as a treatment for medically intractable epilepsy in brain tumor patients A case controlled study using the VNS therapy Patient Outcome Registry Patel KS Labar DR Gordon CM Hassnain KH Schwartz TH Seizure 2013 Oct 22 8 627 33 doi 10 1016 j seizure 2013 04 017 Epub 2013 Jun 12 PMID 23768541 PubMed in process Related citations Facilitative effects of VNS on the motor threshold implications for its antidepressive mode of action Müller HH Reulbach U Maler JM Kornhuber J Sperling W J Neural Transm 2013 Oct 120 10 1507 10 doi 10 1007 s00702 013 1043 8 Epub 2013 Jun 5 PMID 23736944 PubMed in process Related citations Possible usefulness of tianeptine in treatment resistant depression Tobe EH Rybakowski JK Int J Psychiatry Clin Pract 2013 Oct 17 4 313 6 doi 10 3109 13651501 2013 798418 Epub 2013 May 20 PMID 23668804 PubMed in process Related citations Vagal nerve stimulation without dissecting the carotid sheath during intraoperative neuromonitoring of the recurrent laryngeal nerve in thyroid surgery Wu CW Dionigi G Chen HC Chen HY Lee KW Lu IC Chang PY Hsiao PJ Ho KY Chiang FY Head Neck 2013 Oct 35 10 1443 7 doi 10 1002 hed 23154 Epub 2012 Sep 18 PMID 22987562 PubMed in process Related citations VNS publications overview Deze pagina delen Print deze pagina Professionals Voor iedereen die werkt met of voor mensen met epilepsie Forum Forum EpilepsiePlus Activiteiten Professionals Medische zorg Publicaties niet medicamenteuze behandelingen Nervus

    Original URL path: http://www.epilepsievereniging.nl/professionals/medische-sector/publicaties-niet-medicamenteuze-behandelingen/nervus-vagus-stimulatie/additional-publications-october-2013/ (2016-01-11)
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  • Guideline update VNS - Epilepsie Vereniging Nederland
    studies VNS is associated with a 50 seizure reduction in 55 95 Ci 46 64 OF 113 PATIENTS WITH Lennox Gastaut syndrome LGS 4 class III studies VNS is associated with an increase in 50 seizure reduction rates of 7 from 1 5 years postimplantation 2 class III studies VNS is associated with a significant improvement in standard mood scales in 31 adults with epilepsy 2 class III studies Infection risk at the VNS implantation site in children is increased relative to that in adults odds ratio 3 4 95 Ci 1 0 11 2 VNS is possibly effective for seizures both partial and generalized in children for LGS associated seizures and for mood problems in adults with epilepsy VNS may have improved efficacy over time Conclusions VNS may be considered for seizures in children for LGS associated seizures and for improving mood in adults with epilepsy Level C VNS may be considered to have improved efficacy over time Level C Children should be carefully monitored for site infection after VNS implantation http www ncbi nlm nih gov pubmed 23986299 Comments reviewer Prof Van Nieuwenhuizen This is an important paper in particular for paediatric neurologists In the 1999 AAN American Academy of Neurology technology assessment indication for VNS was only given for children 12 years with medically intractable partial seizures who are not candidates for potentially curative surgical resections such as lesionectomies or mesial temporal lobectomies At that time no recommendation could be given for VNS therapy in children 12 years or children with Lennox Gastaut Syndrome LGS That recommendation is now put forward an important message for doctors treating these children Important is also the finding that the responder rate 50 reduction of seizures in children with LGS does not appear to differ from that of the general population of patients with refractory epilepsy Another important statement of this update is that VNS may show improved efficacy over time as it is well known that both drug efficacy and efficacy of epilepsy surgery may decrease over time No evidence could be found for better outcome of VNS therapy using rapid stimulation cycles 7 seconds on and 30 seconds off instead of 30 seconds on and 300 seconds off As rapid cycle will hasten the time for battery expensive replacement this is an important issue Finally special care is requested for handling the device in children in particular developmentally delayed Unpredictable behaviour scratching of the implantation wound wrestling does increase the risk for infection VNS publications overview Deze pagina delen Print deze pagina Professionals Voor iedereen die werkt met of voor mensen met epilepsie Forum Forum EpilepsiePlus Activiteiten Professionals Medische zorg Publicaties niet medicamenteuze behandelingen Nervus Vagus Stimulatie VNS Vagus nerve stimulation for drug resistant epilepsy Treatment of epilepsy by stimulation of the vagus nerve from Head and Neck surgical point of view Vagus nerve stimulation magnet activation for seizures The long term effect of VNS on QoL in patients with pharmacoresistant focal epilepsy Palliative epilepsy surgery in Aicardi syndrome

    Original URL path: http://www.epilepsievereniging.nl/professionals/medische-sector/publicaties-niet-medicamenteuze-behandelingen/nervus-vagus-stimulatie/guideline-update-nvs/ (2016-01-11)
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  • VNS in children - Epilepsie Vereniging Nederland
    or more Of these four 25 had a reduction of more than 80 Seven children 44 had no reduction in their seizure frequency although two of these patients reported benefit regarding seizure control and post ictal recovery The VNS system was removed in two patients due to infection and no benefit respectively Half of the cohort 50 reduced the number of anti epileptic drugs post surgery and there was an overall mean reduction of AED of 0 5 Conclusion This study suggests that VNS is a safe and effective adjuvant therapy in children under 12 years old with over half reporting significant benefit Further studies are needed to enable preoperative selection of patients in order to maximise the potential benefit http www ncbi nlm nih gov pubmed 23681311 Comments reviewer Prof Van Nieuwenhuizen Studies in children below the age of 12 years are scarce so this study is welcome to learn about efficacy and side effects of VNS in young children On the other hand this study has several limitations the number of patients is modest 16 and with regards to epilepsy diagnosis causes syndromes there is much heterogeneity The proposed McHugh classification is not generally accepted as preferred classification for the efficacy of VNS therapy VNS publications overview Deze pagina delen Print deze pagina Professionals Voor iedereen die werkt met of voor mensen met epilepsie Forum Forum EpilepsiePlus Activiteiten Professionals Medische zorg Publicaties niet medicamenteuze behandelingen Nervus Vagus Stimulatie VNS Vagus nerve stimulation for drug resistant epilepsy Treatment of epilepsy by stimulation of the vagus nerve from Head and Neck surgical point of view Vagus nerve stimulation magnet activation for seizures The long term effect of VNS on QoL in patients with pharmacoresistant focal epilepsy Palliative epilepsy surgery in Aicardi syndrome Neuroimaging and electroencephalographic changes after VNS Additional publications

    Original URL path: http://www.epilepsievereniging.nl/professionals/medische-sector/publicaties-niet-medicamenteuze-behandelingen/nervus-vagus-stimulatie/vns-in-children/ (2016-01-11)
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  • Callosotomy vs VNS - Epilepsie Vereniging Nederland
    patient Results The final mean stimuli intensity was 3 0 mA in the Group 2 patients Seizure free patients accounted for 10 in Group 1 and none in Group 2 Ten and sixteen percent of the Group 1 and 2 patients respectively were non responders Improvements in attention and quality of life were noted in 85 of both Group 1 and 2 patients Rupture of the secondary bilateral synchrony was noted in 85 of Group 1 patients there was no EEG modification after VNS in Group 2 Both procedures were effective regarding the control of atypical absences and generalised tonic clonic seizures Both procedures were not effective in controlling tonic seizures Callosotomy was very effective in reducing the frequency of atonic seizures but VNS was ineffective In contrast callosotomy was not effective in reducing myoclonic seizures whereas VNS was Discussion Callosotomy might be preferred as the primary treatment in children with Lennox Gastaut syndrome and no specific findings on MRI if atonic seizures prevail in the patient s clinical picture when myoclonic seizures prevail the same might hold true in favour of VNS When atypical absence or generalised tonic clonic seizures are the main concern although both procedures carry similar effectiveness VNS might be considered a good option as an initial approach taking into account the adverse event profile Patients should be advised that both procedures are not very effective in the treatment of tonic seizures http www ncbi nlm nih gov pubmed 23490456 Comments reviewer Prof Van Nieuwenhuizen Treatment of Lennox Gastaut Syndrome LGS is a challenge for neuro pediatricians Anti epileptic drug treatment AED is often unsuccessful and administration of combinations of AED s is the rule with all subsequent side effects Callosotomy is used as a final attempt to improve quality of life However callosotomy is an invasive procedure with risks of considerable morbidity and rarely mortality Moreover efficacy of callosotomy is variably reported The most invalidating seizure type in LGS is atonic seizures The child may harm itself when falling down traumatic brain injury is not an exemption Callosotomy is reported to be effective in reducing number of atonic fits where VNS is not In a child refractory to AED treatment and ketogenic diet therapy callosotomy may be the next step If callosotomy cannot be performed or if it has been proven to be ineffective VNS may offer a better quality of life reducing number of atypical absences and generalized tonic clonis fits not of atonic fits VNS publications overview Deze pagina delen Print deze pagina Professionals Voor iedereen die werkt met of voor mensen met epilepsie Forum Forum EpilepsiePlus Activiteiten Professionals Medische zorg Publicaties niet medicamenteuze behandelingen Nervus Vagus Stimulatie VNS Vagus nerve stimulation for drug resistant epilepsy Treatment of epilepsy by stimulation of the vagus nerve from Head and Neck surgical point of view Vagus nerve stimulation magnet activation for seizures The long term effect of VNS on QoL in patients with pharmacoresistant focal epilepsy Palliative epilepsy surgery in Aicardi syndrome Neuroimaging and electroencephalographic

    Original URL path: http://www.epilepsievereniging.nl/professionals/medische-sector/publicaties-niet-medicamenteuze-behandelingen/nervus-vagus-stimulatie/callosotomy-vs-vns/ (2016-01-11)
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  • Additional Publications September 2013 - Epilepsie Vereniging Nederland
    with malignant migrating partial seizures in infancy Ishii A Shioda M Okumura A Kidokoro H Sakauchi M Shimada S Shimizu T Osawa M Hirose S Yamamoto T Gene 2013 Dec 1 531 2 467 71 doi 10 1016 j gene 2013 08 096 Epub 2013 Sep 10 PMID 24029078 PubMed in process Related citations The role of vagus nerve overactivity in the increased incidence of pneumonia following traumatic brain injury Hall S Kumaria A Belli A Br J Neurosurg 2013 Sep 12 Epub ahead of print PMID 24024980 PubMed as supplied by publisher Related citations Vagal modulation of cardiac ventricular arrhythmia Ng GA Exp Physiol 2013 Sep 27 Epub ahead of print PMID 24014808 PubMed as supplied by publisher Related citations Comparing the effects of cortical resection and vagus nerve stimulation in patients with nonlesional extratemporal epilepsy Kuba R Novák Z Chrastina J Pažourková M Hermanová M Ošlejšková H Rektor I Brázdil M Epilepsy Behav 2013 Sep 28 3 474 80 doi 10 1016 j yebeh 2013 05 036 Epub 2013 Jul 25 PMID 23892577 PubMed in process Related citations Vagus nerve stimulation in refractory epilepsy new indications and outcome assessment Marras CE Chiesa V De Benedictis A Franzini A Rizzi M Villani F Ragona F Tassi L Vignoli A Freri E Specchio N Broggi G Casazza M Canevini MP Epilepsy Behav 2013 Sep 28 3 374 8 doi 10 1016 j yebeh 2013 05 021 Epub 2013 Jul 6 PMID 23835092 PubMed in process Related citations Transcutaneous auricular vagus nerve stimulation as a complementary therapy for pediatric epilepsy a pilot trial He W Jing X Wang X Rong P Li L Shi H Shang H Wang Y Zhang J Zhu B Epilepsy Behav 2013 Sep 28 3 343 6 doi 10 1016 j yebeh 2013 02 001 Epub 2013 Jun 29 PMID 23820114 PubMed in process Related citations Vagus nerve stimulation for chronic major depressive disorder 12 month outcomes in highly treatment refractory patients Christmas D Steele JD Tolomeo S Eljamel MS Matthews K J Affect Disord 2013 Sep 25 150 3 1221 5 doi 10 1016 j jad 2013 05 080 Epub 2013 Jun 29 PMID 23816447 PubMed in process Related citations Lipid rich enteral nutrition regulates mucosal mast cell activation via the vagal anti inflammatory reflex de Haan JJ Hadfoune M Lubbers T Hodin C Lenaerts K Ito A Verbaeys I Skynner MJ Cailotto C van der Vliet J de Jonge WJ Greve JW Buurman WA Am J Physiol Gastrointest Liver Physiol 2013 Sep 305 5 G383 91 doi 10 1152 ajpgi 00333 2012 Epub 2013 Jun 27 PMID 23812038 PubMed in process Related citations The effects of stimulation parameters on clinical outcomes in patients with vagus nerve stimulation implants with major depression Müller HH Kornhuber J Maler JM Sperling W J ECT 2013 Sep 29 3 e40 2 doi 10 1097 YCT 0b013e318290f7ed PMID 23728236 PubMed in process Related citations The clinical utility of different quantitative methods for measuring treatment resistance in major depression Hazari H

    Original URL path: http://www.epilepsievereniging.nl/professionals/medische-sector/publicaties-niet-medicamenteuze-behandelingen/nervus-vagus-stimulatie/additional-publications-september-2013/ (2016-01-11)
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  • Ketogeen Dieet - Epilepsie Vereniging Nederland
    Forum Forum EpilepsiePlus Activiteiten Professionals Medische zorg Publicaties niet medicamenteuze behandelingen Nervus Vagus Stimulatie VNS Ketogeen Dieet Epilepsiechirurgie Deep Brain Stimulation Tandheelkundige zorg Onderwijs Zorg Therapeuten Werk Epilepsie Vereniging Nederland EVN Postbus 258 3990 GB Houten Bezoekadres De Molen 35 Telefoon 030 63 440 62 E mail info epilepsievereniging nl Tijd voor vernieuwing Om deze webpagina foutloos te kunnen bekijken hebt u een recentere internetbrowser nodig U kunt een nieuwe

    Original URL path: http://www.epilepsievereniging.nl/professionals/medische-sector/publicaties-niet-medicamenteuze-behandelingen/ketogeen-dieet/ (2016-01-11)
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  • Epilepsiechirurgie - Epilepsie Vereniging Nederland
    Forum EpilepsiePlus Activiteiten Professionals Medische zorg Publicaties niet medicamenteuze behandelingen Nervus Vagus Stimulatie VNS Ketogeen Dieet Epilepsiechirurgie Deep Brain Stimulation Tandheelkundige zorg Onderwijs Zorg Therapeuten Werk Epilepsie Vereniging Nederland EVN Postbus 258 3990 GB Houten Bezoekadres De Molen 35 Telefoon 030 63 440 62 E mail info epilepsievereniging nl Tijd voor vernieuwing Om deze webpagina foutloos te kunnen bekijken hebt u een recentere internetbrowser nodig U kunt een nieuwe internetbrowser

    Original URL path: http://www.epilepsievereniging.nl/professionals/medische-sector/publicaties-niet-medicamenteuze-behandelingen/epilepsiechirurgie/ (2016-01-11)
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  • Deep Brain Stimulation - Epilepsie Vereniging Nederland
    epilepsie Forum Forum EpilepsiePlus Activiteiten Professionals Medische zorg Publicaties niet medicamenteuze behandelingen Nervus Vagus Stimulatie VNS Ketogeen Dieet Epilepsiechirurgie Deep Brain Stimulation Tandheelkundige zorg Onderwijs Zorg Therapeuten Werk Epilepsie Vereniging Nederland EVN Postbus 258 3990 GB Houten Bezoekadres De Molen 35 Telefoon 030 63 440 62 E mail info epilepsievereniging nl Tijd voor vernieuwing Om deze webpagina foutloos te kunnen bekijken hebt u een recentere internetbrowser nodig U kunt een

    Original URL path: http://www.epilepsievereniging.nl/professionals/medische-sector/publicaties-niet-medicamenteuze-behandelingen/deep-brain-stimulation/ (2016-01-11)
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