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  • wings 15g note 902
    Note 902 A mathematical constructive counterpart it has in the electronic arrangements which are described today Back to main text

    Original URL path: http://www.metafysica.nl/wings/wings_15g_note902.html (2016-02-01)
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  • wings 15g note 905
    case of crystalline periodicity and amorphous homogeneity the retroaction becomes uniform and the change with increasing size soon approaches zero Growth i e increase in size in both periodic and homogeneous bodies does not change the qualitative content of such a body whereas in true molecules dead or alive addition or subtraction always brings with it a qualitative change A satisfactory answer clarifying the nature of the bonding condition is

    Original URL path: http://www.metafysica.nl/wings/wings_15g_note905.html (2016-02-01)
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  • wings 15g note 914
    Unimol we do not speak of individual separate molecules but of typical parts of the one living molecule parts which we may happily call proteins or even protein molecules As to denaturation there is a marked poly aetiology meaning that there are many causes of denaturation In many respects it is similar to a melting event It is endothermic meaning that it in order to take place takes up energy from the environment but is nevertheless spontaneous at lower temperatures for the driving force in denaturation is the strong increase of entropy heat not able to perform work in the process of rearranging and increase of entropy is always spontaneous The activation energy is high in denaturation because a substantial number of H bridges has to be broken On the other hand one believes that denaturation reducible to an extensive scattering of the weak bonding system between the amino acid side chains doesn t need the breaking up of a large number of hydrogen bonds within the polypeptid helix so that the protein molecule essentially is preserved as to its configuration In denaturation one also speaks of unfolding and meaning with it a rearrangement of figuration A series of physical changes appearing in denaturation are not unconditionally characteristic for they may be restored by some follow up treatment without however the other lost properties such as biological activity serological specifity and others reappearing again A far reaching renaturation succeeds in certain crystallizable proteins such as hemoglobine serumalbumine trypsine etc but also here irreversible changes have remained recognizable by the fact that they may more easily be split up by enzymes have higher chemical sensitivity etc Renaturation reversible denaturation in the usual sense is as to vital substance certainly totally out of the question Both kinds of denaturation respectively the substrates

    Original URL path: http://www.metafysica.nl/wings/wings_15g_note914.html (2016-02-01)
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  • wings 15g note 915
    open to us the relevant body of knowledge is still not sufficient to clearly apprehend the phenomenon of denaturation or even to carry out the reverse process This simply reflects the fact that we can define denaturation only negatively and

    Original URL path: http://www.metafysica.nl/wings/wings_15g_note915.html (2016-02-01)
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  • wings 15g note 916
    916 The image of oppositeness and of polarity is ineradicably cherished and only gradually replaced by the much more useful plastic and proper concept of correlative complementarity Back to main

    Original URL path: http://www.metafysica.nl/wings/wings_15g_note916.html (2016-02-01)
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  • wings 15g note 917
    service Various stock proteins which can be mobilized at any time are perhaps intermediate in this respect One author holds that the protoplasm is involved in a subtle interaction of coagulation and anti coagulation factors This is acceptable if one

    Original URL path: http://www.metafysica.nl/wings/wings_15g_note917.html (2016-02-01)
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  • wings 15g note 918
    problem with the origin of Life not however questioning the event of origin as such after one has found an opening towards the origin of life already in the easiest way namely with the help of probability within a vast

    Original URL path: http://www.metafysica.nl/wings/wings_15g_note918.html (2016-02-01)
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  • wings 15g note 919
    is individually compositionally as a result of constant molecular exchange only of a statistical nature Here only unspecific summational and superpositional effects are possible at all i e a liquid of any size that is bulk liquid and especially its boundary layer is it is true something else than the single molecule from a multitude of which that layer is composed but nevertheless still something similar The new qualities rather direct reduce to the individual molecule and may derived from it directly So for example surfactant molecules soap molecules see Introduction above They lump up together with their equivalent ends and may in this way form micelles separating inside from outside In living substance this is quite different Here also the surface layer has despite a supposed weak to and fro swinging of the vital phase boundary here Müller places a question mark as well as metabolic exchanges an organ like enduring nature For here it is about the boundary between the living and non living state Just as in the case of the surface layer of a liquid one should to begin with also imagine the denaturation membrane as coarse chemically equivalent to or identical with the substrate lying

    Original URL path: http://www.metafysica.nl/wings/wings_15g_note919.html (2016-02-01)
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